| small GTPase regulator activity |
8 x 10-18 |
255 |
| GTPase activator activity |
2 x 10-17 |
223 |
| Ras guanyl-nucleotide exchange factor activity |
2 x 10-15 |
93 |
| GTPase regulator activity |
2 x 10-15 |
401 |
| nucleoside-triphosphatase regulator activity |
2 x 10-15 |
413 |
| Ras GTPase activator activity |
5 x 10-15 |
101 |
| enzyme activator activity |
1 x 10-14 |
357 |
| SH3 domain binding |
2 x 10-13 |
114 |
| phospholipid binding |
6 x 10-13 |
212 |
| phosphatidylinositol-3,4,5-trisphosphate binding |
5 x 10-12 |
16 |
| phosphatidylinositol binding |
1 x 10-11 |
133 |
| ARF GTPase activator activity |
3 x 10-11 |
22 |
| phosphatidylinositol-3,4-bisphosphate binding |
3 x 10-11 |
12 |
| Rho guanyl-nucleotide exchange factor activity |
4 x 10-11 |
71 |
| Rho GTPase activator activity |
7 x 10-11 |
34 |
| guanyl-nucleotide exchange factor activity |
1 x 10-10 |
169 |
| GTPase binding |
2 x 10-10 |
140 |
| sugar binding |
5 x 10-10 |
181 |
| lipid binding |
8 x 10-10 |
433 |
| actin binding |
8 x 10-10 |
310 |
| protein homodimerization activity |
9 x 10-10 |
474 |
| actin filament binding |
2 x 10-9 |
57 |
| small GTPase binding |
3 x 10-9 |
124 |
| growth factor activity |
3 x 10-9 |
151 |
| non-membrane spanning protein tyrosine kinase activity |
3 x 10-9 |
44 |
| Rac GTPase activator activity |
8 x 10-9 |
12 |
| cysteine-type endopeptidase activity |
2 x 10-8 |
70 |
| protein tyrosine kinase activity |
2 x 10-8 |
477 |
| binding, bridging |
3 x 10-8 |
132 |
| signaling adaptor activity |
3 x 10-8 |
63 |
| protein binding, bridging |
6 x 10-8 |
123 |
| MHC protein binding |
9 x 10-8 |
16 |
| fibroblast growth factor receptor binding |
10 x 10-8 |
18 |
| Rab GTPase activator activity |
1 x 10-7 |
46 |
| kinase binding |
1 x 10-7 |
335 |
| phosphoric ester hydrolase activity |
2 x 10-7 |
352 |
| phosphotyrosine binding |
2 x 10-7 |
14 |
| protein kinase binding |
3 x 10-7 |
292 |
| SH3/SH2 adaptor activity |
5 x 10-7 |
50 |
| carbohydrate kinase activity |
5 x 10-7 |
20 |
| Ras GTPase binding |
6 x 10-7 |
112 |
| antigen binding |
6 x 10-7 |
32 |
| Rac GTPase binding |
8 x 10-7 |
15 |
| Rho GTPase binding |
9 x 10-7 |
47 |
| GDP binding |
1 x 10-6 |
28 |
| protein kinase C activity |
1 x 10-6 |
15 |
| apoptotic protease activator activity |
2 x 10-6 |
19 |
| calcium-dependent phospholipid binding |
2 x 10-6 |
19 |
| cysteine-type peptidase activity |
2 x 10-6 |
129 |
| phospholipid transporter activity |
6 x 10-6 |
29 |
| oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor |
6 x 10-6 |
11 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
7 x 10-6 |
105 |
| phosphatase activity |
7 x 10-6 |
247 |
| cytokine receptor activity |
8 x 10-6 |
78 |
| ADP binding |
1 x 10-5 |
22 |
| tumor necrosis factor receptor superfamily binding |
1 x 10-5 |
35 |
| cysteine-type endopeptidase activator activity involved in apoptotic process |
1 x 10-5 |
17 |
| ligand-gated channel activity |
2 x 10-5 |
128 |
| ligand-gated ion channel activity |
2 x 10-5 |
128 |
| aminopeptidase activity |
2 x 10-5 |
30 |
| cytoskeletal adaptor activity |
2 x 10-5 |
20 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amid... |
2 x 10-5 |
30 |
| receptor signaling protein activity |
2 x 10-5 |
106 |
| extracellular-glutamate-gated ion channel activity |
2 x 10-5 |
19 |
| tumor necrosis factor-activated receptor activity |
2 x 10-5 |
10 |
| sequence-specific DNA binding RNA polymerase II transcription factor activity |
2 x 10-5 |
188 |
| protein tyrosine phosphatase activity |
2 x 10-5 |
102 |
| ionotropic glutamate receptor activity |
3 x 10-5 |
18 |
| death receptor activity |
3 x 10-5 |
12 |
| metal ion transmembrane transporter activity |
5 x 10-5 |
276 |
| serine-type exopeptidase activity |
5 x 10-5 |
10 |
| inorganic cation transmembrane transporter activity |
5 x 10-5 |
351 |
| RNA polymerase II transcription factor binding transcription factor activity |
5 x 10-5 |
58 |
| DNA-directed RNA polymerase activity |
6 x 10-5 |
37 |
| RNA polymerase activity |
6 x 10-5 |
37 |
| calcium-dependent cysteine-type endopeptidase activity |
6 x 10-5 |
15 |
| pattern recognition receptor activity |
6 x 10-5 |
15 |
| monovalent inorganic cation transmembrane transporter activity |
7 x 10-5 |
290 |
| excitatory extracellular ligand-gated ion channel activity |
7 x 10-5 |
49 |
| hydrolase activity, acting on glycosyl bonds |
7 x 10-5 |
104 |
| potassium ion transmembrane transporter activity |
8 x 10-5 |
138 |
| SNAP receptor activity |
8 x 10-5 |
20 |
| extracellular ligand-gated ion channel activity |
9 x 10-5 |
68 |
| tumor necrosis factor receptor binding |
1 x 10-4 |
23 |
| deaminase activity |
1 x 10-4 |
25 |
| potassium channel activity |
1 x 10-4 |
123 |
| calcium-release channel activity |
2 x 10-4 |
13 |
| monosaccharide binding |
2 x 10-4 |
53 |
| receptor signaling protein serine/threonine kinase activity |
2 x 10-4 |
52 |
| hormone activity |
2 x 10-4 |
97 |
| inward rectifier potassium channel activity |
2 x 10-4 |
22 |
| divalent inorganic cation transmembrane transporter activity |
2 x 10-4 |
50 |
| lipid transporter activity |
2 x 10-4 |
59 |
| chemoattractant activity |
2 x 10-4 |
12 |
| double-stranded RNA binding |
2 x 10-4 |
35 |
| inositol phosphate phosphatase activity |
2 x 10-4 |
14 |
| lipoprotein particle receptor activity |
3 x 10-4 |
15 |
| nucleobase-containing compound kinase activity |
3 x 10-4 |
43 |
| protein phosphatase inhibitor activity |
3 x 10-4 |
22 |
| MAP kinase kinase kinase activity |
3 x 10-4 |
19 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WGAGGAAG which mat... |
2 x 10-10 |
158 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RGAGGAARY which ma... |
3 x 10-10 |
347 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNRTAATNANNN whic... |
3 x 10-10 |
154 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RNWMBAGGAART which... |
4 x 10-9 |
162 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif YCATTAA. Motif doe... |
6 x 10-9 |
403 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NWATAAGTATWT which... |
6 x 10-9 |
152 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WTGAAAT. Motif doe... |
6 x 10-9 |
431 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TAAYNRNNTCC. Motif... |
1 x 10-8 |
124 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RCAGGAAGTGNNTNS wh... |
3 x 10-8 |
174 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif KRCAGGAARTRNKT whi... |
3 x 10-8 |
199 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NMTTCATAAWTATWNMNA... |
4 x 10-8 |
167 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif YTACTTCCTG which m... |
5 x 10-8 |
152 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NWRARYAAAYANN whic... |
10 x 10-8 |
142 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WNNANATAAAYANNNN w... |
2 x 10-7 |
134 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ACWTCCK which matc... |
2 x 10-7 |
172 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNCATCAATCAANNW wh... |
3 x 10-7 |
105 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NGGCTCYATCAYC. Mot... |
4 x 10-7 |
160 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CACCRATANNTATBG wh... |
4 x 10-7 |
36 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NATYGATSSS which m... |
5 x 10-7 |
168 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif DGATADGAHWAGATA wh... |
6 x 10-7 |
177 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WNNANYYAATTANCNN w... |
8 x 10-7 |
183 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNKGAATTAVAVTDN wh... |
1 x 10-6 |
186 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ANANTTTTATKRCC whi... |
2 x 10-6 |
185 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ANNCACTTCCTG which... |
2 x 10-6 |
172 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTAAGTRSTT which m... |
3 x 10-6 |
131 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNYTTCCY which mat... |
3 x 10-6 |
182 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CTWAWGTAAACANWGN w... |
4 x 10-6 |
108 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNNNTTCTKGGA. Mot... |
4 x 10-6 |
182 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WGARYCAGCTGYGGNCNK... |
4 x 10-6 |
181 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif YRNCAGGAAGYRNSTBDS... |
5 x 10-6 |
172 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTATGYTAAT which m... |
7 x 10-6 |
184 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RAAAAWTANNNNNNNNNN... |
7 x 10-6 |
156 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNTAATTAGCNNN whi... |
10 x 10-6 |
176 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTACGTAA which mat... |
1 x 10-5 |
116 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNTAATTNNCATTANCN... |
1 x 10-5 |
159 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNGTTGTTTACNTN whi... |
2 x 10-5 |
186 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TNYTGGGAATACC. Mot... |
2 x 10-5 |
156 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif MGGAAGTG which mat... |
3 x 10-5 |
488 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TMTRWRAGGRSS which... |
3 x 10-5 |
196 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GGGGGTTGACGYANA. M... |
3 x 10-5 |
99 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GTTACRYAAT which m... |
3 x 10-5 |
180 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CGGAARNGGCNG. Moti... |
3 x 10-5 |
32 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif SYATTGTG. Motif do... |
3 x 10-5 |
155 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNARGNCANNNTGACCYN... |
4 x 10-5 |
197 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GTANTNN which matc... |
4 x 10-5 |
81 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CTGRYYYNATT. Motif... |
5 x 10-5 |
49 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNTTCCN which mat... |
5 x 10-5 |
110 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTAYRTAA which mat... |
5 x 10-5 |
177 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif AAAYRNCTG. Motif d... |
5 x 10-5 |
277 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NTGGNNNNNNGCCAANN ... |
6 x 10-5 |
195 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CWNAWTKWSATRYN whi... |
6 x 10-5 |
192 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TGCGCANK. Motif do... |
7 x 10-5 |
344 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif SYTACGTCAC which m... |
7 x 10-5 |
189 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CWTAATTG which mat... |
7 x 10-5 |
195 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif BCNNNRNGCANBGNTGNR... |
8 x 10-5 |
109 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTANWNANTGGM. Moti... |
8 x 10-5 |
44 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NATTGTTTATWT which... |
8 x 10-5 |
177 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NCNRNNGRCNGTTGGKGG... |
9 x 10-5 |
170 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNAAASNN which ma... |
1 x 10-4 |
185 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RNCTGNYNRNCTGNY. M... |
1 x 10-4 |
47 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GCATAAWTTAT which ... |
1 x 10-4 |
170 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNCWGATARNNNN whic... |
1 x 10-4 |
172 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GKCRGKTT which mat... |
1 x 10-4 |
169 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif YNNNTAATCYCMN whic... |
2 x 10-4 |
189 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif KNNTRTTTRTTTA whic... |
2 x 10-4 |
143 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTCNRGNNNNTTC. Mot... |
2 x 10-4 |
105 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CAGTTTCWCTTTYCC wh... |
2 x 10-4 |
163 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CAGNYGKNAAA. Motif... |
2 x 10-4 |
53 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif AGATAAGATAN which ... |
2 x 10-4 |
128 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif AYMATAATATTTKN whi... |
2 x 10-4 |
163 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ATGAATAAWT which m... |
2 x 10-4 |
170 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif GTCATNNWNNNNN whic... |
2 x 10-4 |
160 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TWSGCGCGAAAAYKR. M... |
2 x 10-4 |
52 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TNNTTGTTTACNTW whi... |
2 x 10-4 |
169 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif WCTCNATGGY. Motif ... |
3 x 10-4 |
49 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NGAANNWTCK which m... |
3 x 10-4 |
166 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTTSGCGS. Motif do... |
3 x 10-4 |
157 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NCWGATAACA which m... |
3 x 10-4 |
193 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TBTGCACHCGGCCC whi... |
3 x 10-4 |
181 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ATGTTWAYATAA which... |
3 x 10-4 |
175 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNCAMAACACRNA whi... |
3 x 10-4 |
144 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TGTCTGTCT which ma... |
3 x 10-4 |
175 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NTTSGCGG which mat... |
4 x 10-4 |
167 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NGATAAGNMNN which ... |
4 x 10-4 |
193 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNNNNCNNTNTGTNCTN... |
4 x 10-4 |
187 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ASMCTTGGGSRGGG whi... |
4 x 10-4 |
181 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NAWTTCCN which mat... |
4 x 10-4 |
177 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif ATGMATWWATTCAT whi... |
4 x 10-4 |
79 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNNTTCACGCWTGANTK... |
4 x 10-4 |
71 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TCCATTKW. Motif do... |
5 x 10-4 |
167 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif CAGCCAATGAG which ... |
5 x 10-4 |
171 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNNNGATANKGNN whi... |
5 x 10-4 |
169 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TWTTTAATTGGTT whic... |
5 x 10-4 |
169 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif RAARTGAAACTG which... |
5 x 10-4 |
179 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTTSGCGSG which ma... |
5 x 10-4 |
162 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNANNGTAAACAANNN w... |
5 x 10-4 |
185 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif NNNNNNCGTCACGSTYNN... |
6 x 10-4 |
59 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif MGTTACYAGGCAAM whi... |
6 x 10-4 |
189 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif TTTSGCGSG which ma... |
6 x 10-4 |
159 |
| promoter regions [-2kb,2kb] around transcr. start site cont. motif AGAANRTTCN which m... |
6 x 10-4 |
180 |